Endocrine Abstracts

Purpose: The primary aim of this study was to evaluate changes in the diameter and volume of thyroid cancer nodules identified using fine-needle aspiration biopsy (FNAB) or surgery, and to compare the changes in size between thyroid cancer nodules and benign nodules. The secondary aim was to analyze the risk factors associated with thyroid cancer nodule growth.Methods: A total of 96 patients with 102 nodules were enrolled in the cancer group, and 98 pati...

Background: In the previous study, it was demonstrated that pancreatic steatosis was significantly associated with subclinical atherosclerosis in patients with non-obese T2DM. As the result, it was suggested that pancreatic steatosis might be related to macrovascular complication of T2DM. However, the association of pancreatic steatosis on microvascular complication of T2DM has been unknown.Objective: This study aimed to investigate the relation between ...

Background: Although sclerostin (SOST) and Dickkopf-related protein 1 (DKK1) are major regulators in bone metabolism, the associations between these soluble Wnt antagonists and osteoporotic fracture (OF) in Asians, who may have distinct biologic characteristics with Caucasians, are inconclusive. Furthermore, there have been no clinical studies separately considering non-vertebral and vertebral fractures in terms of the blood levels of SOST and DKK1.Metho...

Objective: Obesity is a well-known risk factor for type 2 diabetes, but few data exist on the association between weight changes and future diabetes risk in non-obese subjects. This study aimed to investigate the effect of weight changes on the incidence of type 2 diabetes in Korea, using prospective nationwide data.Research design and methods: A total of 51 405 non-diabetic subjects were included who had undergone health examinations in 2002 and complet...